Going by experience, it helps greatly to block news communities, or at least the domains or users that have a predilection for sharing misery, fear, envy, and all the doom “goodness”. Also requires being able to identify such places and people, but I’d imagine a small pain at the moment is much better than to have your filter polluted and grinding your gears slowly enough that when you get to have enough, you’re at the verge of snapping. And if using RSS feeds, since those usually don’t have custom feeds applied¹, Ublock Origin for hiding the whole post based on who posted or what site it links to helps too.

¹Lemmy has RSS feeds for any given user’s feed btw.